Two Common Eye Diseases with Genetic Links

Do you have family members with eye-related conditions?

The two main eye diseases in adults that have a genetic link are glaucoma and age-related macular degeneration (AMD).

Glaucoma is a deterioration of the optic nerve caused by pressure in the eye or poor blood flow to the optic nerve. It has no symptoms at its onset. In most cases if you wait to get glaucoma diagnosed until you begin to realize there is something wrong with your vision, upwards of 70% of your optic nerve will have already been destroyed. Once the nerve is destroyed there is no way of reversing that today and treatment is focused on trying to preserve whatever nerve tissue is left.

Your chances of getting glaucoma are four to 10 times higher if you have a close relative with glaucoma. Getting your eyes examined regularly is always important but even more so if there is a family history of glaucoma.

Macular degeneration is the leading cause of blindness in most of the developed world. It too can cause serious vision loss if you wait until you have significant symptoms before a diagnosis. There are now some preventative treatments for AMD--the earlier it is detected the better off you will be.

Having a close family member with AMD may increase your chances of having the disease as much as 50 percent, making timely diagnosis and treatment imperative.

Other eye diseases that run in families include strabismus (crossed eyes), myopia (nearsightedness), hyperopia (farsightedness), and astigmatism.

All of these family connections are important to know so that you and your eye doctor can together take the best possible care of your eyes. Before your next eye exam, ask your relatives if they have a history of eye disease. It might not make for the lightest of conversation at your next family gathering, but it could help save your vision.

Dry Eye Risk Factors

Millions of people are affected by dry eye syndrome and the prevalence of dry eye increases with age. An estimated 3.2 million women and over and 1.68 million men age 50 and over are affected by dry eye syndrome.

Here are some risk factors for dry eye:

Aging: Advancing age is the single most important risk factor for dry eye. Most of our body’s moisture-producing glands produce less moisture as we age.

Gender: Women are twice as likely as men to suffer from dry eye. Changes in hormone levels throughout your lifetime often affect the amount of moisture produced by the lacrimal glands that produce tears.

Medical problems: Several diseases result in increased risk for dry eye syndrome, including rheumatoid arthritis, diabetes, thyroid abnormalities, asthma, cataracts, glaucoma, and lupus.

Medication: Certain medications can decrease the body's ability to produce lubricating tears.

Contact lenses: Dry eye is the leading cause of contact lens discomfort or intolerance.

Environmental conditions: Exposure to smoke, fluorescent lights, air pollution, wind, heat, air conditioning, and dry climates can increase tear evaporation.

Computer users: People who spend many hours staring at computer screens tend to blink significantly less often. Not blinking allows the eyes to dry faster.

Refractive surgery: This increases the risk of dry eye. Surgery often interferes with the superficial nerves on the cornea. Properly functioning nerves are necessary to help keep the eye surface moist.

Dry eye can present in many different ways. You can have irritation (often presenting as a foreign body feeling on the eye surface), redness, burning, excessive tearing (yes, that sounds counterintuitive but dry eye often presents this way), or intermittent blurring of vision.

The only way to be sure your symptoms are truly a dry eye problem is to have a comprehensive exam by your optometrist. There are other problems, such as allergic reactions and blepharitis, that can create similar symptoms so you need to be examined to determine which of these issues is causing your symptoms.

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